Thymic hyperplasia in Graves′ disease

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Thymic hyperplasia in Graves' disease

Debora Lucia Seguro Danilovic, Regina Matsunaga Martin, Pedro Caruso, Suemi Marui I Hospital das Clı́nicas da Faculdade de Medicina da Universidade de São Paulo, Unidade de Tireoide, Endocrinology and Metabolism Department. São Paulo/SP, Brazil. II Hospital das Clı́nicas da Faculdade de Medicina da Universidade de São Paulo, Endocrinology and Metabolism Department, São Paulo/ SP, Brazil. III Hosp...

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Thymic hyperplasia in patients with Graves' disease.

BACKGROUND Graves' disease (GD) is commonly associated with other autoimmune conditions, and there is also a rare but well documented association between GD and thymic hyperplasia (TH). It is hard to say the real frequency of this latter association because most cases remain asymptomatic and are consequently not thoroughly investigated. MATERIALS AND METHODS We reviewed the literature on GD-r...

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Graves' Patient with Thymic Expression of Thyrotropin Receptors and Dynamic Changes in Thymic Hyperplasia Proportional to Graves' Disease Activity

Thymic hyperplasia is frequently observed in Graves' disease. However, detectable massive enlargement of the thymus is rare, and the mechanism of its formation has remained elusive. This case showed dynamic changes in thymic hyperplasia on serial computed tomography images consistent with changes in serum thyrotropin receptor (TSH-R) antibodies and thyroid hormone levels. Furthermore, the patie...

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Thymic hyperplasia in patients with Graves' disease. Identification of thyrotropin receptors in human thymus.

Thymic size and density were studied in 23 untreated patients with Graves' disease and 38 control subjects using computed tomography. Both thymic size and density were higher in untreated patients with Graves' disease than in control subjects in the age-matched group. After treatment with antithyroid drugs, both thymic size and density were significantly reduced, with a concomitant decrease in ...

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Thymic Hyperplasia Associated with Graves’ Disease in a 10-year-old Boy

Thymic hyperplasia associated with Graves' disease is rarely reported in children, although it is not uncommon in adults. Occasionally, an enlarged thymus presents as an anterior mediastinal mass on a radiographic examination. Such patients often undergo invasive procedures such as a thymus biopsy or thymectomy because of suspected malignancy. However, an enlarged thymus with Graves' disease is...

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ژورنال

عنوان ژورنال: Indian Journal of Endocrinology and Metabolism

سال: 2013

ISSN: 2230-8210

DOI: 10.4103/2230-8210.111676